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Best pain relief for sciatica

Written by Caidr's team of doctors and pharmacists based in UK | Updated: 21.02.2023 | 3 min read

Sciatica is the sensation of pain, tingling, or burning running along the course of the sciatic nerve. This is a large nerve that emerges from the spine, in the lower part of the back, and extends across each buttock to the back of the thigh, the outside edge of the lower leg, and to the foot. You have two sciatic nerves, one coming out from each side of the spine.

Sciatic pain occurs due to compression or inflammation of the sciatic nerve. This may be in response to a sporting or lifting injury to the lower back, prolonged sitting, or sometimes it's caused by a slipped disc.

The specific location of the pain or altered sensation depends on where the nerve is irritated or compressed. Sciatica often resolves on its own, and pain can vary, but it's usually worse in the first few days, and this can be managed with non-drug treatments and painkillers. The best painkillers for your sciatica will often depend on the severity and intensity of the pain, as well as any other health conditions you have and preferences for types of treatment.

Non-drug treatment

Taking things easy and resting for the first few days can help to relieve pain brought on by an acute episode of sciatica. If sleeping is difficult, try some altered positions, like having a pillow under your knees if you sleep on your back. Or, if you are a side sleeper, try with a pillow between your legs or under your hips.

After this initial period of rest, it's important for recovery to introduce gentle exercise, so try gentle movements with appropriate pain relief. This means going about your day-to-day activities as normal, as far as you're able.

Alternating between hot and cold compression of the affected area may also help to relieve discomfort, especially muscle spasms associated with sciatica. A licensed chiropractor or physiotherapist may be helpful, as they can provide manipulation to ease the area and targeted exercises to aid recovery.

Targeting mild to moderate pain

Painkillers are useful for treating pain and helping recover from sciatica. Acetaminophen is usually a safe and sensible place to start when reaching for painkillers, with relatively few risks or side effects if taken as instructed. It’s well-tolerated and may be sufficient for mild-moderate pain.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are particularly useful at treating back pain and sciatica, as they are a class of medications that work on pain and reduce inflammation. Examples include ibuprofen and naproxen.

Oral acetaminophen and ibuprofen, and naproxen are available to buy from any pharmacy, but stronger NSAIDs such as diclofenac need a prescription.

After using acetaminophen or an NSAID individually, try using them in combination. This will allow you to cover periods where the painkillers may wear off or add an extra layer of pain relief as they work in different ways on the body.

Targeting severe pain: opioids and prescription medicines

If, after trying a combination of acetaminophen and NSAIDs, you are still experiencing pain, you should speak to your doctor. Your doctor may want to try a short-term trial of opioids.

Side effects of the opioid family of medications include constipation, drowsiness, and feeling dizzy, sick, or slightly “out of it.” Certain people seem more susceptible to this than others.

When should I see my doctor?

If this is your first episode of sciatica or severe lower back or buttock pain, it's worth booking an appointment with your doctor to confirm the diagnosis. Your doctor will examine you, check what you have tried already, and consider prescribing other medications which can help with the pain.

Sciatica usually resolves itself by 6 to 12 weeks, with the worst of the pain starting to improve over the first few weeks. If your pain is not improving after a few weeks despite care and exercise at home, if the pain is severe or getting worse, or if it is affecting your daily activities, you should see your doctor to discuss this.

Signs that suggest you should book an urgent appointment with your doctor are lack of control when peeing or pooping, numbness around the buttocks and rectum, numbness in your legs, weakness of your lower legs, fevers, or other severe symptoms that feel out of proportion with the problem.

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